--- SWIG/_bio.i.orig
+++ SWIG/_bio.i
@@ -293,8 +293,12 @@ int bio_should_write(BIO* a) {
 }
 
 /* Macros for things not defined before 1.1.0 */
-#if OPENSSL_VERSION_NUMBER < 0x10100000L
-static BIO_METHOD *
+#if OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
+
+#if !defined(LIBRESSL_VERSION_NUMBER)
+static
+#endif
+BIO_METHOD *
 BIO_meth_new( int type, const char *name )
 {
     BIO_METHOD *method = malloc( sizeof(BIO_METHOD) );
@@ -306,7 +310,10 @@ BIO_meth_new( int type, const char *name )
     return method;
 }
 
-static void
+#if !defined(LIBRESSL_VERSION_NUMBER)
+static
+#endif
+void
 BIO_meth_free( BIO_METHOD *meth )
 {
     if ( meth == NULL ) {
--- SWIG/_evp.i.orig
+++ SWIG/_evp.i
@@ -19,7 +19,7 @@ Copyright (c) 2009-2010 Heikki Toivonen. All rights re
 #include <openssl/rsa.h>
 #include <openssl/opensslv.h>
 
-#if OPENSSL_VERSION_NUMBER < 0x10100000L
+#if OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
 
 HMAC_CTX *HMAC_CTX_new(void) {
     HMAC_CTX *ret = PyMem_Malloc(sizeof(HMAC_CTX));
--- SWIG/_lib11_compat.i.orig
+++ SWIG/_lib11_compat.i
@@ -8,7 +8,7 @@
  */
 
 %{
-#if OPENSSL_VERSION_NUMBER < 0x10100000L
+#if OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
 
 #include <string.h>
 #include <openssl/engine.h>
--- SWIG/_lib.i.orig
+++ SWIG/_lib.i
@@ -21,7 +21,7 @@
 
 %{
 /* OpenSSL 1.0.2 copmatbility shim */
-#if OPENSSL_VERSION_NUMBER < 0x10002000L
+#if OPENSSL_VERSION_NUMBER < 0x10002000L || defined(LIBRESSL_VERSION_NUMBER)
 typedef void (*OPENSSL_sk_freefunc)(void *);
 typedef void *(*OPENSSL_sk_copyfunc)(const void *);
 typedef struct stack_st OPENSSL_STACK;
@@ -499,7 +499,7 @@ int passphrase_callback(char *buf, int num, int v, voi
 %inline %{
 
 void lib_init() {
-#if OPENSSL_VERSION_NUMBER < 0x10100000L
+#if OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
     SSLeay_add_all_algorithms();
     ERR_load_ERR_strings();
 #endif
--- SWIG/_ssl.i.orig
+++ SWIG/_ssl.i
@@ -275,7 +275,7 @@ const SSL_METHOD *sslv3_method(void) {
 #endif
 
 const SSL_METHOD *tlsv1_method(void) {
-#if OPENSSL_VERSION_NUMBER >= 0x10100000L
+#if OPENSSL_VERSION_NUMBER >= 0x10100000L && !defined(LIBRESSL_VERSION_NUMBER)
     PyErr_WarnEx(PyExc_DeprecationWarning,
                  "Function TLSv1_method has been deprecated.", 1);
 #endif
--- SWIG/_threads.i.orig
+++ SWIG/_threads.i
@@ -5,7 +5,7 @@
 #include <pythread.h>
 #include <openssl/crypto.h>
 
-#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L
+#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
 #define CRYPTO_num_locks()      (CRYPTO_NUM_LOCKS)
 static PyThread_type_lock lock_cs[CRYPTO_num_locks()];
 static long lock_count[CRYPTO_num_locks()];
@@ -13,7 +13,7 @@ static int thread_mode = 0;
 #endif
 
 void threading_locking_callback(int mode, int type, const char *file, int line) {
-#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L
+#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
         if (mode & CRYPTO_LOCK) {
                 PyThread_acquire_lock(lock_cs[type], WAIT_LOCK);
                 lock_count[type]++;
@@ -25,7 +25,7 @@ void threading_locking_callback(int mode, int type, co
 }
 
 unsigned long threading_id_callback(void) {
-#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L
+#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
     return (unsigned long)PyThread_get_thread_ident();
 #else
     return (unsigned long)0;
@@ -35,7 +35,7 @@ unsigned long threading_id_callback(void) {
 
 %inline %{
 void threading_init(void) {
-#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L
+#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
     int i;
     if (!thread_mode) {
         for (i=0; i<CRYPTO_num_locks(); i++) {
@@ -50,7 +50,7 @@ void threading_init(void) {
 }
 
 void threading_cleanup(void) {
-#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L
+#if defined(THREADING) && OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
     int i;
     if (thread_mode) {
         CRYPTO_set_locking_callback(NULL);
--- SWIG/libcrypto-compat.h.orig
+++ SWIG/libcrypto-compat.h
@@ -1,7 +1,7 @@
 #ifndef LIBCRYPTO_COMPAT_H
 #define LIBCRYPTO_COMPAT_H
 
-#if OPENSSL_VERSION_NUMBER < 0x10100000L
+#if OPENSSL_VERSION_NUMBER < 0x10100000L || defined(LIBRESSL_VERSION_NUMBER)
 
 #include <openssl/rsa.h>
 #include <openssl/dsa.h>